Impact of COVID-19 on thrombus composition and response to thrombolysis: Insights from a monocentric cohort population of COVID-19 patients with acute ischemic stroke.

Jean-Philippe DésillesMialitiana Solo NomenjanaharyArturo ConsoliVéronique OllivierDorothée FailleMarie-Charlotte BourrienneMylène HamdaniSébastien DupontLucas Di MeglioSimon EscalardBenjamin MaierRaphael BlancMichel PiotinBertrand LapergueNadine AjzenbergMarc VasseMikael MazighiBenoît Ho Ho Tin Noénull null

Published in: Journal of thrombosis and haemostasis : JTH (2022)

These results show that COVID-19 does not impact NETs content or worsen fibrinolysis resistance of AIS thrombi, a therapeutic hurdle that could be overcome by DNase 1 even in the context of SARS-CoV-2 infection.

Keyphrases

acute ischemic stroke
coronavirus disease
sars cov
respiratory syndrome coronavirus
pulmonary embolism