Oxidized soluble guanylyl cyclase causes erectile dysfunction in alcoholic mice.

Miguel A OlivenciaLeticia Gil de Biedma-ElduayenPablo Giménez-GómezBianca BarreiraArgentina FernándezJavier AnguloMaria Isabel ColadoEsther O'Shea Francisco Pérez Vizcaíno

Published in: British journal of pharmacology (2023)

Our results demonstrate that alcoholic mice show ED in vitro and in vivo due to an alteration of the redox state of sGC and suggest that sGC activators may be effective in ED associated with alcoholism.

Keyphrases

emergency department
high fat diet induced
liver injury
wild type
skeletal muscle
insulin resistance
low density lipoprotein