Irregular red blood cell antibodies, abnormal hemoglobin and dangerous universal blood donor insights from a public blood center in a Brazilian metropolitan area.
Laiane da Silva SantosSérgio Eduardo Soares FernandesAnna Luiza Oliveira Sant'AnnaFlávio Ferreira Pontes AmorimFelipe Ferreira Pontes AmorimFábio Ferreira AmorimPublished in: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis (2024)
Anti-A/anti-B hemolysins in O group donors, abnormal hemoglobin and irregular RBC antibodies pose risks to transfusion practice and should not be overlooked. Advancing age, female sex, ABO blood group other than O, or Rh(D)- negative are independently associated with the presence of irregular RBC antibodies. Dangerous universal blood donors were associated with advanced age, female gender, Rh(D)-positive blood type, and individuals residing in a Brazilian state other than where the blood center was located.