Pralidoxime-Induced Potentiation of the Pressor Effect of Adrenaline and Hastened Successful Resuscitation by Pralidoxime in a Porcine Cardiac Arrest Model.

Hyoung Youn LeeNajmiddin MamadjonovKyung Woon JeungYong Hun JungByung Kook LeeKyung-Sub MoonTag HeoYong Il Min

Published in: Cardiovascular drugs and therapy (2020)

Pralidoxime improved CPP and hastened ROSC in a model with a short duration of untreated VF. The potentiation of the pressor effect of adrenaline was not accompanied by the worsening of the adverse effects of adrenaline.

Keyphrases

cardiac arrest
cardiopulmonary resuscitation
high glucose
oxidative stress
stress induced