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Next-generation sequencing of residual cytologic fixative preserved DNA from pancreatic lesions: A pilot study.

Clifton G FulmerKyung ParkThomas DilcherMai HoSusanna MirabelliSusan AlpersteinErika M HissongMeredith PittmanMomin T SiddiquiJonas J HeymannRhonda K YantissAlain C BorczukHelen D FernandesCarlie S SigelWei SongJuan Miguel MosqueraRema Rao
Published in: Cancer cytopathology (2020)
Residual DNA from alcohol-fixed aspirates are an underutilized source for NGS. Sequencing residual fixative-derived DNA has the potential to be integrated into the workup of pancreatic aspirates, possibly impacting management.
Keyphrases
  • circulating tumor
  • cell free
  • single molecule
  • circulating tumor cells
  • nucleic acid
  • gene expression
  • risk assessment
  • genome wide