Neuroplasticity: The Continuum of Change.
Rachel WallaceDavid E OlsonJacob M HookerPublished in: ACS chemical neuroscience (2023)
Neuroplasticity is a term that is increasingly permeating mainstream discourse and being used by the popular press to simplify descriptions of how the brain changes in response to stimuli such as exercise, sleep, food, drugs of abuse, and medicines, among others. However, it is a complex, multifaceted concept representing a continuum connecting molecular, cellular, and circuit-level changes and their effects on human behavior. In this Viewpoint, we examine neuroplasticity from several perspectives to construct a holistic view of this ambiguous term. By engaging experts across various scientific disciplines, we attempt to provide an easy entry point to the concept of neuroplasticity for readers of ACS Chemical Neuroscience . By highlighting how neuroplasticity changes in both health and disease, we demonstrate that the concept is applicable to both adaptive and maladaptive responses to stimuli, underscoring its significance in chemical neuroscience.
Keyphrases
- preterm infants
- endothelial cells
- physical activity
- public health
- healthcare
- acute coronary syndrome
- mental health
- resting state
- white matter
- risk assessment
- human health
- health information
- sleep quality
- brain injury
- induced pluripotent stem cells
- cerebral ischemia
- functional connectivity
- climate change
- depressive symptoms
- resistance training
- subarachnoid hemorrhage
- intimate partner violence