PIWI silencing mechanism involving the retrotransposon nimbus orchestrates resistance to infection with Schistosoma mansoni in the snail vector, Biomphalaria glabrata.
Michael SmithSwara YadavOlayemi G FagunloyeNana Adjoa PelsDaniel A HortonNashwah AlsultanAndrea BornsCarolyn CousinFreddie DixonVictoria H MannClarence LeePaul J BrindleyNajib El SayedJoanna Mary BridgerMatty KnightPublished in: PLoS neglected tropical diseases (2021)
These findings support a role for the interplay of BgPiwi and nimbus in the epigenetic modulation of plasticity of resistance/susceptibility in the snail-schistosome relationship.