Phosphorus Radical-Initiated Cascade Reaction To Access 2-Phosphoryl-Substituted Quinoxalines.
Yan LiuXiao-Lan ChenFan-Lin ZengXiao-Lan ChenChen QuLu-Lu FanZi-Long AnRui LiChun-Feng JingSheng-Kai WeiLing-Bo QuBing YuYuan-Qiang SunYu-Fen ZhaoPublished in: The Journal of organic chemistry (2018)
An effective radical cascade cyclization strategy was developed, by which a wide range of 2-phosphoryl-substituted quinoxalines were prepared in one pot via reaction of ortho-diisocyanoarenes with diarylphosphine oxides in the presence of AgNO3 under mild reaction conditions.