Safety of User-Initiated Intensification of Insulin Delivery Using Cambridge Hybrid Closed-Loop Algorithm.
Julia WareMalgorzata E WilinskaYue RuanJanet M AllenCharlotte K BoughtonSara HartnellLia BallyCarine de BeaufortRachel Elizabeth Jane BesserFiona M CampbellKatharine DraxlbauerDaniela ElleriMark L EvansElke Fröhlich-ReitererAtrayee GhatakSabine E HoferThomas M KapellenLalantha LeelarathnaJulia Katharina MaderWomba M MubitaParth NarendranTina PoettlerBirgit Rami-MerharMartin TauschmannTabitha RandellHood ThabitAjay ThankamonyNicola TrevelyanRoman HovorkaPublished in: Journal of diabetes science and technology (2022)
Use of an algorithm intensification mode in HCL therapy is safe across all age groups with type 1 diabetes. The higher time in hyperglycemia observed on "Boost" days suggests that users are more likely to use algorithm intensification on days with extreme hyperglycemic excursions.