Neurobiological findings associated with high cognitive performance in older adults: a systematic review.

Wyllians Vendramini BorelliLucas Porcello SchillingGraciane RadaelliLuciana Borges FerreiraLeonardo PisaniMirna Wetters PortuguezJaderson Costa da Costa

Published in: International psychogeriatrics (2018)

Structural and molecular brain preservation of older adults with high cognitive performance may be associated with brain maintenance. The operationalized definition of high-performing older adults must be carefully addressed using appropriate age cut-off and cognitive evaluation, including memory and non-memory tests. Further studies with a longitudinal approach that include a younger control group are essential.

Keyphrases

physical activity
white matter
working memory
resting state
cerebral ischemia
subarachnoid hemorrhage