Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples.

Zandra C Félix GarzaMichael LenzJoerg LiebmannGökhan ErtaylanMatthias BornIlja C W ArtsPeter A J HilbersNatal A W van Riel

Published in: BMC medical genomics (2019)

Our analysis demonstrates the value of this new resource in interpreting skin-derived transcriptomics data by enabling the direct quantification of cell types in a skin sample and the characterization of pathological changes in tissue composition.

Keyphrases

soft tissue
single cell
wound healing
oxidative stress
big data
stem cells
bone marrow
mesenchymal stem cells
microbial community
antibiotic resistance genes