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Unravelling lung adenocarcinoma in an immunocompetent patient with endobronchial aspergilloma: A case report.

Khai Lip NgNai-Chien HuanWei Loon TanNur Husna Mohd AminudinFazilah HassanKasuma Mohamed Nordin
Published in: Respirology case reports (2024)
Inhalation of Aspergillus spp. can cause a wide spectrum of lung diseases. Endobronchial aspergilloma is an uncommon clinical entity that occurs because of Aspergillus spp. overgrowth in the airway lumen. We present a 73-year-old gentleman with a rare dual pathology of endobronchial aspergilloma and endobronchial adenocarcinoma. He initially presented with prolonged cough, dyspnoea, and haemoptysis. Bronchoscopy revealed an obstructed right main bronchus by a necrotic mass whereby histological examination showed evidence of Aspergillus spp. infection. The lesion however persisted despite treatment with anti-fungal agents. Repeated bronchoscopy and biopsy eventually unravelled an underlying endobronchial adenocarcinoma. He received chemotherapy but ultimately passed away 3 months later.
Keyphrases
  • ultrasound guided
  • fine needle aspiration
  • squamous cell carcinoma
  • locally advanced
  • cell wall
  • radiation therapy