Blood Biomarkers and 6- to 7-Year Childhood Outcomes Following Neonatal Encephalopathy.
Athina PappasSeetha ShankaranScott A McDonaldWaldemar A CarloAbbot R LaptookJon E TysonAbhik DasKristin SkogstrandDavid M HougaardRosemary D HigginsPublished in: American journal of perinatology (2020)
· Elevation of specific cytokines and chemokines in neonates with encephalopathy has been noted along with increased risk of neurodevelopmental impairment in infancy.. · Cytokine/chemokines at <7 days were assessed among neonates in a trial of hypothermia for HIE.. · Neonates who died or were impaired at 6 to 7 years following hypoxic-ischemic encephalopathy had lower RANTES and higher MCP-1 levels than those who survived without impairment..