Differences in medication adherence by sex and organ type among adolescent and young adult solid organ transplant recipients.
Yulia VaisbourdMourad DahhouXun ZhangRuth Sapir-PichhadzeHeloise CardinalOlwyn JohnstonTom David Blydt-HansenLee Anne TibblesLorraine HamiwkaSimon UrschelPatricia BirkJanice BissonnetteMina Matsuda-AbediniJennifer Harrison BScPhmJeffrey SchiffVeronique PhanSabina De GeestUpton D AllenYaron AvitzurSeema MitalBethany J FosterPublished in: Pediatric transplantation (2022)
Females show better self-reported adherence than males but greater variability in tacrolimus levels. Social desirability bias, more common in females than males, may contribute to better self-reported adherence among females. Higher tacrolimus variability among females may reflect biologic differences in tacrolimus metabolism between males and females rather than sex differences in adherence. There were no significant differences in adherence by organ type.