Efficient synthesis and unit-selective π-extension of π-fused [4.3.3]propellane as a chiral building block.
Kenichi KatoSeigo TanakaNobuyoshi SetoKeisuke WadaMasayuki GonShixin FaShunsuke OhtaniKazuo TanakaTomoki OgoshiPublished in: Chemical communications (Cambridge, England) (2023)
A three-dimensional skeleton, π-fused [4.3.3]propellane, was constructed and derivatized by selective π-extension at the two naphthalene units. The obtained propellanes existed as stereoisomers different in spatial arrangement, one of which displayed a chiroptical response originating from through-space interactions between 5-azachrysenes in a skew position.