Risk of Infection with Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis.
Fausto PetrelliAnna Maria MorelliAndrea LucianiAntonio GhidiniCinzia SolinasPublished in: Targeted oncology (2021)
Compared to CT alone, ICIs were safer and are recommended for frail patients. Conversely, CT + ICIs or ICIs combinations increased infection risk. Further studies are required to identify high-risk patients and evaluate the need for CT dose reduction or prophylactic myeloid growth factors.