Opportunistic Infections in Patients with Inflammatory Bowel Disease Treated with Advanced Therapies: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Different mechanisms of action may have specific OIs profiles. In the absence of a uniform definition of OIs, these estimates are less reliable. We propose a definition to be used in future studies to help standardized reporting. When using this definition, we saw significant differences in incidence rates of OIs across mechanisms of action.