Early prognostic factors in septic shock cancer patients: a prospective study with a proteomic approach.
D MokartColombe SaillardC ZemmourM BisbalA SanniniL Chow-ChineJ-P BrunM FaucherJ-M BoherY ToironC ChabannonJ-P BorgA GonçalvesL CamoinPublished in: Acta anaesthesiologica Scandinavica (2018)
Endothelial dysfunction, revealed by proteomics, appears as an independent prognostic factor on day-30 mortality, as well as hydric balance, acute respiratory failure and bacteremia, in critically ill cancer patients admitted to the intensive care unit. Endothelial failure is underestimated in clinical practice and represents an innovative therapeutic target.
Keyphrases
- prognostic factors
- respiratory failure
- septic shock
- clinical practice
- extracorporeal membrane oxygenation
- mechanical ventilation
- papillary thyroid
- label free
- mass spectrometry
- cardiovascular events
- squamous cell
- acute respiratory distress syndrome
- endothelial cells
- risk factors
- intensive care unit
- gram negative
- type diabetes
- squamous cell carcinoma
- multidrug resistant
- young adults
- drug induced
- aortic dissection