A new triazine based π-conjugated mesoporous 2D covalent organic framework: its in vitro anticancer activities.

Sabuj Kanti DasSnehasis MishraKrishnendu MannaUtpal KayalSupratim MahapatraKrishna Das SahaSasanka DalapatiG P DasAmany A MostafaAsim Bhaumik

Published in: Chemical communications (Cambridge, England) (2018)

We report a new highly crystalline 2D π-conjugated hexagonal mesoporous covalent organic framework material, TrzCOF, through the solvothermal polycondensation of 1,3,5-tri(4-formylbiphenyl) benzene [Ph7(CHO)3, TFBPB] with 2,4,6-tris(4-aminophenyl)-1,3,5-triazine (TAPT) and it displayed excellent anticancer activity for human colorectal carcinoma HCT-116 cells.

Keyphrases

cell cycle arrest
induced apoptosis
photodynamic therapy
endothelial cells
cell death
water soluble
solid phase extraction
induced pluripotent stem cells
metal organic framework
highly efficient
endoplasmic reticulum stress
high resolution
cell proliferation