Prevalence and risk factors for left ventricular diastolic dysfunction in systemic sclerosis: a multi-center study of CRDC cohort in China.
Min HuiJiaxin ZhouLiyun ZhangXinwang DuanMengtao LiQian WangJiuliang ZhaoYong HouDong XuXiaofeng ZengPublished in: Clinical rheumatology (2021)
LV diastolic dysfunction was prevalent in the SSc population. Advanced onset age, PAH, positive anti-RNP antibody, increased WBC count, and adverse metabolic status were independent risk factors for SSc-related LVDD. Key Points • In this Chinese multi-center cohort of systemic sclerosis, LVDD is not a rare complication, with a prevalence of 31.4%. • The presence of advanced onset age, PAH, positive anti-RNP antibody, increased WBC count and adverse metabolic status were baseline predictors of developing LVDD in SSc.
Keyphrases
- systemic sclerosis
- left ventricular
- interstitial lung disease
- heart failure
- blood pressure
- oxidative stress
- hypertrophic cardiomyopathy
- acute myocardial infarction
- cardiac resynchronization therapy
- aortic stenosis
- left atrial
- ejection fraction
- peripheral blood
- mitral valve
- risk factors
- polycyclic aromatic hydrocarbons
- emergency department
- rheumatoid arthritis
- acute coronary syndrome