Cell-Based Therapies for the Treatment of Shoulder and Elbow Tendinopathies: A Scoping Review.
Berardo Di MatteoRiccardo RanieriAngelo MancaSimone CappatoMaurilio MarcacciElizaveta KonAlessandro CastagnaPublished in: Stem cells international (2021)
All the papers included suggested a beneficial role of cell-based approaches to treat common upper limb tendinopathies, with an overall satisfactory safety profile. However, the lack of high-level evidence and the presence of controversial issues, such as interproduct variability, harvest source, and application strategies, do not allow standardization of these novel biologic approaches, whose efficacy needs to be confirmed with properly designed randomized trials.