Successful Thrombolysis despite Having an Incidental Unruptured Cerebral Aneurysm.
Diana Briosa E GalaAndré AlmeidaNadine Monteiro Salgueiro AraújoAna Paiva NunesPatrícia FerreiraNuno MendonçaAlexandre Amaral-SilvaJoão AlcântaraPublished in: Case reports in neurological medicine (2014)
Purpose. To report a case of successful thrombolysis performed in a patient with an incidental unruptured intracranial aneurysm and review the literature. Case Report. Patient admitted for ischemic stroke due to left posterior cerebral artery occlusion, with an incidental right middle cerebral artery aneurysm, who underwent treatment with tissue plasminogen activator (rtPA) resulting in clinical improvement without complications. Conclusion. The presence of unruptured intracranial aneurysms is considered as a contraindication to thrombolysis, due to a potentially higher hemorrhagic risk of aneurysm rupture. Patients, otherwise, eligible for thrombolysis are usually excluded from receiving this emergent treatment, despite its potential benefits. A reevaluation of the strict exclusion criteria for thrombolysis in acute stroke patients should be considered.
Keyphrases
- middle cerebral artery
- pulmonary embolism
- case report
- acute ischemic stroke
- coronary artery
- internal carotid artery
- subarachnoid hemorrhage
- systematic review
- ejection fraction
- newly diagnosed
- liver failure
- atrial fibrillation
- prognostic factors
- combination therapy
- patient reported outcomes
- hepatitis b virus
- drug induced
- endovascular treatment
- blood brain barrier
- respiratory failure
- patient reported
- cerebral blood flow