Developing an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies.
Jianbo TianMing ZhangFuwei ZhangKai GaoZequn LuYimin CaiCan ChenCaibo NingYanmin LiSangni QianHao BaiYizhuo LiuHeng ZhangShuoni ChenXiangpan LiYongchang WeiBin LiYing ZhuJinhua YangMingjuan JinXiaoping MiaoKun ChenPublished in: Genome medicine (2024)
Our comprehensive risk-stratified model in population-based CRC screening trials represents a promising advancement in personalized risk assessment, facilitating tailored CRC screening in the EAS population. This approach enhances the transferability of PRSs across ancestries and thereby helps address health disparity.