An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease.

M Furkan BurakGurol TuncmanAyse Nur AyciKashish ChetalGrace Yankun Lee SeropianKaren InouyeZon Weng LaiNurdan DagtekinRuslan I SadreyevElliot IsraelGökhan S Hotamışlıgil

Published in: bioRxiv : the preprint server for biology (2024)

Investigating FABP4's pivotal role in obesity-driven airway disease, this study unveils an adipo-pulmonary axis with potential therapeutic implications.

Keyphrases

insulin resistance
metabolic syndrome
pulmonary hypertension
weight loss
type diabetes
high fat diet induced
weight gain
binding protein
high glucose
adipose tissue
diabetic rats
drug induced
endothelial cells
oxidative stress