Multiple combinations of melanocytic and vascular endothelial markers enhance the detection rate of lymphovascular invasion in cutaneous melanoma.
Aysel BayramSule Ozturk SariYasemin OzlukFaruk TasNesimi BuyukbabaniPublished in: Journal of cutaneous pathology (2020)
The recognition of LVI is improved by dual IHC and predicts SLN metastasis. The detection of LVI using dual IHC, especially by a combination of CD31/S100 and D2-40/S100 is a useful step that inclusion should be recommended in basic evaluation parameters for cutaneous melanoma.