Imaging Characteristics and First Experience of [68Ga]THP-PSMA, a Novel Probe for Rapid Kit-Based Ga-68 Labeling and PET Imaging: Comparative Analysis with [68Ga]PSMA I&T.

Thorsten DerlinSebastian SchmuckCathleen JuhlSteffi TeichertJohanna ZörgiebelHans-Jürgen WesterSophie M SchneefeldAlmut C A WalteJames T ThackerayTobias L RossFrank M Bengel

Published in: Molecular imaging and biology (2019)

[68Ga]THP-PSMA yields suitable in vivo uptake characteristics. The simplified synthesis method for [68Ga]THP-PSMA may facilitate wider application and higher patient throughput with PSMA imaging. However, direct intraindividual comparison studies are needed to assess the relative performance of [68Ga]THP-PSMA vs other PSMA ligands in terms of clinical detection rate and image quality.

Keyphrases

pet ct
positron emission tomography
pet imaging
high resolution
image quality
computed tomography
magnetic resonance
magnetic resonance imaging
loop mediated isothermal amplification
mass spectrometry
quantum dots
sensitive detection
case control