Current Status and Perspectives of Diagnosis and Treatment of Periprosthetic Joint Infection.
Haotian ZhouYaji YangYanhao ZhangFeilong LiYidong ShenLeilei QinWei HuangPublished in: Infection and drug resistance (2024)
Periprosthetic joint infection (PJI) is a catastrophic complication following joint replacement surgery, posing significant challenges to orthopedic surgeons. Due to the lack of a definitive diagnostic gold standard, timely treatment initiation is problematic, resulting in substantial economic burdens on patients and society. In this review, we thoroughly analyze the complexities of PJI and emphasize the importance of accurate diagnosis and effective treatment. The article specifically focuses on the advancements in diagnostic techniques, ranging from traditional pathogen culture to advanced molecular diagnostics, and discusses their role in enhancing diagnostic accuracy. Additionally, we review the latest surgical management strategies, including everything from debridement to revision surgeries. Our summary aims to provide practical information for the diagnosis and treatment of PJI and encourages further research to improve diagnostic accuracy and treatment outcomes.
Keyphrases
- end stage renal disease
- current status
- minimally invasive
- total hip arthroplasty
- newly diagnosed
- total knee arthroplasty
- ejection fraction
- chronic kidney disease
- total hip
- peritoneal dialysis
- squamous cell carcinoma
- mass spectrometry
- acute coronary syndrome
- health information
- smoking cessation
- surgical site infection