Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development.

Laura Lopez-SanzSusana BernalLuna Jimenez-CastillaIgnacio PrietoSara La MannaSergio Gomez-LopezLuis Miguel Blanco-ColioJesus EgidoJose Luis Martin-VenturaCarmen Gomez-Guerrero

Published in: Clinical and translational medicine (2022)

Our findings provide insight into the role and mechanisms mediating IgG-FcγR-associated inflammation and aortic wall injury in AAA, which might represent therapeutic targets against AAA disease.

Keyphrases

abdominal aortic aneurysm
oxidative stress
aortic valve
pulmonary artery
coronary artery
binding protein
atrial fibrillation
aortic dissection