Data integration from pathology slides for quantitative imaging of multiple cell types within the tumor immune cell infiltrate.
Zhaoxuan MaStephen L ShiaoEmi J YoshidaSteven SwartwoodFangjin HuangMichael E DocheAlice P ChungBeatrice S KnudsenArkadiusz GertychPublished in: Diagnostic pathology (2017)
In summary, we developed a general method to integrate data from IHC stained slides into a single dataset. Because of the transfer error between slides, we recommend applying the antibody for demarcation of the tumor on the same slide as the ICI antibodies.