New insights into pediatric community-acquired pneumonia gained from untargeted metabolomics: A preliminary study.
Giovanni Del BorrelloMatteo StoccheroGiuseppe GiordanoPaola PirilloStefania ZanconatoLiviana Da DaltSilvia CarraroSusanna EspositoEugenio BaraldiPublished in: Pediatric pulmonology (2019)
This preliminary study suggests that viral and pneumococcal pneumonia differently affect the systemic metabolome, with a stronger disruption of the adrenal steroid pathway in pneumococcal pneumonia. This finding may lead to the discovery of novel diagnostic biomarkers and bring us closer to personalized therapy for pCAP.