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New insights into pediatric community-acquired pneumonia gained from untargeted metabolomics: A preliminary study.

Giovanni Del BorrelloMatteo StoccheroGiuseppe GiordanoPaola PirilloStefania ZanconatoLiviana Da DaltSilvia CarraroSusanna EspositoEugenio Baraldi
Published in: Pediatric pulmonology (2019)
This preliminary study suggests that viral and pneumococcal pneumonia differently affect the systemic metabolome, with a stronger disruption of the adrenal steroid pathway in pneumococcal pneumonia. This finding may lead to the discovery of novel diagnostic biomarkers and bring us closer to personalized therapy for pCAP.
Keyphrases
  • community acquired pneumonia
  • mass spectrometry
  • sars cov
  • high throughput
  • liquid chromatography
  • young adults
  • extracorporeal membrane oxygenation
  • drug induced
  • acute respiratory distress syndrome