Tumour organoids and assembloids: Patient-derived cancer avatars for immunotherapy.
Jie MeiXingjian LiuHui-Xiang TianYixuan ChenYang CaoJun ZengYung-Chiang LiuYaping ChenYang GaoJi-Ye YinPeng-Yuan WangPublished in: Clinical and translational medicine (2024)
The current PDTO models have not yet constructed key cellular and non-cellular components. PDTOs should be expandable and editable. PDTOs are promising preclinical models for immunotherapy unless mature PDTOs can be established. PDTO biobanks with consensual standards are urgently needed.