Minimum Alveolar Concentration of Isoflurane in Rats Chronically Treated with the Synthetic Cannabinoid WIN 55,212-2.
Julio Raul Chavez-MonteagudoJosé Antonio IbancovichiPedro Sánchez-AparicioSergio Recillas-MoralesJorge Osorio-AvalosMarco Antonio De Paz-CamposPublished in: Animals : an open access journal from MDPI (2022)
The administration of WIN 55,212-2 for 21 days increases the MAC of isoflurane in rats. This effect does not disappear 8 days after discontinuation of treatment with the synthetic cannabinoid.
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