Diabetes impairs the haemodynamic response to non-selective betablockers in compensated cirrhosis and predisposes to hepatic decompensation.
Rafael PaternostroMathias JachsLukas HartlBenedikt SimbrunnerBernhard ScheinerDavid Josef Maria BauerPhilipp SchwablGeorg SemmlerMichael TraunerMattias MandorferThomas ReibergerPublished in: Alimentary pharmacology & therapeutics (2023)
In patients with cACLD, diabetes and a higher BMI impair the HVPG-response to NSBB. Furthermore, diabetes-independently from Child B and lack of HVPG-response-increases the risk of hepatic decompensation.