Kinetics of HE4 and CA125 as prognosis biomarkers during neoadjuvant chemotherapy in advanced epithelial ovarian cancer.
Jorge Adan Alegría-BañosJosé C Jiménez-LópezArely Vergara-CastañedaDavid F Cantú de LeónAlejandro Mohar-BetancourtDelia Pérez-MontielGisela Sánchez-DomínguezMariana García-VillarejoCésar Olivares-PérezÁngel Hernández-ConstantinoAcitlalin González-SantiagoMiguel Clara-AltamiranoLiz Arela-QuispeDiddier PradaPublished in: Journal of ovarian research (2021)
Serum HE4 levels were independently associated with TR among patients with AOEC treated with NACT, also a reduction between baseline HE4 and first chemotherapy levels was also independently associated with the TR. These findings might be relevant for predicting a lack of response to treatment.