Characterization of Plasma Immunoglobulin G Responses in Elite Neutralizers of Human Cytomegalovirus.
Melissa J HarnoisMaria DennisDagmar StöhrSarah M ValenciaNicole RodgersEleanor C SemmesHelen S WebsterJennifer A JenksRichard BarfieldJustin PollaraCliburn ChanChristian SinzgerSallie R PermarPublished in: The Journal of infectious diseases (2022)
We conclude that antibody responses against multiple glycoprotein specificities may be needed to achieve potent plasma neutralization and that potently HCMV elite-neutralizing plasma antibodies can also mediate polyfunctional responses.