Early drivers of clonal hematopoiesis shape the evolutionary trajectories of de novo acute myeloid leukemia.

Ryan D ChowPriya VeluSafoora DeihimiJonathan BelmanAngela YounNisargbhai ShahSelina M LugerMartin P CarrollJennifer MorrissetteRobert L Bowman

Published in: medRxiv : the preprint server for health sciences (2024)

mutations persist through AML-directed therapy Distinct CH-related mutations shape the evolutionary trajectories of AML from diagnosis through relapse.

Keyphrases

acute myeloid leukemia
allogeneic hematopoietic stem cell transplantation
depressive symptoms
genome wide
room temperature
gene expression
dna methylation
acute lymphoblastic leukemia
drug induced
cell therapy