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Genomic analysis reveals independent evolution of Plasmodium falciparum populations in Ethiopia.

Deriba AberaCaleb K KibetTeshome DegefaLucas Amenga-EtegoJoel L BargulLemu Golassa
Published in: Malaria journal (2021)
Plasmodium falciparum populations in the central region of Ethiopia was structurally diverged from both Southeast Asian and other East African populations. Malaria infections in Ethiopia had low within-host diversity, and parasites carry fixed chloroquine resistance markers despite the withdrawal of this drug for the treatment of P. falciparum.
Keyphrases
  • plasmodium falciparum
  • genetic diversity
  • emergency department
  • copy number
  • gene expression
  • genome wide