Past, present, and future of Lyme disease vaccines: antigen engineering approaches and mechanistic insights.
Wen-Hsiang ChenUlrich StrychMaria Elena BottazziYi-Pin LinPublished in: Expert review of vaccines (2022)
Over the past two decades, several new genetically redesigned Lyme disease vaccine candidates have shown success in both preclinical and clinical settings and built a solid foundation for further development. These studies have greatly informed the protective mechanisms of reducing Lyme disease burdens and ending the endemic of this disease.
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