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Case report: a 10-year-old girl with primary hypoparathyroidism and systemic lupus erythematosus.

Hanna Borysewicz-SańczykBeata SawickaJustyna MichalakJerzy WójtowiczElżbieta DobreńkoJerzy KonstantynowiczE Helen KempRajesh V ThakkerJeremy AllgroveFadil M HannanJanusz Dzięcioł
Published in: Journal of pediatric endocrinology & metabolism : JPEM (2021)
Objectives Hypoparathyroidism is a rare disease in children that occurs as a result of autoimmune destruction of the parathyroid glands, a defect in parathyroid gland development or secondary to physical parathyroid gland disturbance. Typical symptoms of hypoparathyroidism present as hypocalcaemia and hyperphosphatemia due to decreased parathyroid hormone secretion and may lead to nerve and muscles disturbances resulting in clinical manifestation of tetany, arrhythmias and epilepsy. Currently, there is no conventional hormone replacement treatment for hypoparathyroidism and therapeutic approaches include normalising mineral levels using an oral calcium supplement and active forms of vitamin D. Case presentation We present the case of a 10-year-old girl with primary hypoparathyroidism who had no prior history of autoimmune disorders, but who subsequently developed systemic lupus erythematosus.
Keyphrases
  • systemic lupus erythematosus
  • case report
  • disease activity
  • multiple sclerosis
  • young adults
  • physical activity
  • mental health
  • drug induced
  • combination therapy
  • soft tissue