Lipschütz acute vulvar ulcer related to COVID-19 vaccination: First case report in South America.
Lucero Sangster-CarrascoRomario Paz-TemocheJulia Cristina Coronado ArroyoMarcio José Concepción-ZavaletaPela J RoseboomLuis Alberto Concepción UrteagaFrancisca Elena Zavaleta GutiérrezPublished in: Medwave (2023)
Lipschütz ulcer is a non-sexually transmitted genital lesion of unknown etiology, which presents as a painful vulvar ulcer. Lipschütz ulcers have been described in most continents. This is the first case reported in Peru and South America. We present the case of a 33-year-old female patient with a Lipschütz ulcer after being vaccinated with the second dose of the AstraZeneca COVID-19 vaccine. She reported having had only one sexual partner in her lifetime. Laboratory results were negative for herpes simplex 2, Cytomegalovirus, Toxoplasma gondii, Epstein-Barr virus, and syphilis. The patient received symptomatic treatment. Ten days after the onset, the patient was significantly better during follow-up. This case report displays a potential adverse effect of the AstraZeneca COVID-19 vaccine as a Lipschütz ulcer triggered by the host humoral immune response. However, further research is needed to establish the causal relationship between these two.
Keyphrases
- case report
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- coronavirus disease
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- immune response
- toxoplasma gondii
- diffuse large b cell lymphoma
- human immunodeficiency virus
- liver failure
- mental health
- respiratory syndrome coronavirus
- emergency department
- squamous cell carcinoma
- toll like receptor
- radiation therapy
- early stage
- inflammatory response
- human health
- hiv infected
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