Facile Preparation of Hierarchically Porous Monolith with Optical Activity Based on Helical Substituted Polyacetylene via One-Step Synthesis for Enantioselective Crystallization.

The present study reported the flexible and highly efficient one-step synthesis of chiral hierarchical porous monoliths via cross-linking and polymerization-induced phase separation using substituted acetylene and cross-linker in the presence of porogenic solvent (tetrahydrofuran and methanol) in which the complex doping and complicated procedures were not required. It was demonstrated that hierarchical pore structure with through-pore and high surface area existed in the monoliths, which provides more chiral sites and space for interaction between monolithic materials and the solution. The porous structures and pore size can be adjusted by changing the conditions of phase separation. Moreover, the prepared monoliths exhibited good optical activity, thermal stability and mechanical properties. Therefore, the hierarchically porous monoliths with optical activity were applied in enantioselective crystallization and showed good performance.