Exosomal miR-22-3p from hUCMSCs alleviates OGC apoptosis and improves ovarian function in POF mouse models by targeting KLF6 and ATF4-ATF3-CHOP pathway.
Keyphrases
- mesenchymal stem cells
- umbilical cord
- endoplasmic reticulum stress
- transcription factor
- diffuse large b cell lymphoma
- mouse model
- endothelial cells
- bone marrow
- oxidative stress
- stem cells
- type diabetes
- cell death
- cell cycle arrest
- metabolic syndrome
- polycystic ovary syndrome
- adipose tissue
- high fat diet induced
- insulin resistance
- signaling pathway
- induced pluripotent stem cells
- skeletal muscle