Leptin stimulates tissue rat mast cell pro-inflammatory activity and migratory response.

Paulina ŻelechowskaJustyna AgierSylwia RóżalskaMagdalena WiktorskaElżbieta Kozłowska

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2018)

Our observations clearly documented that leptin promotes the pro-inflammatory activity of mast cells, and it thereby engages these cells in the inflammatory processes.

Keyphrases

induced apoptosis
oxidative stress
cell cycle arrest
signaling pathway