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Bibliometric analysis of organoids in regenerative medicine-related research worldwide over two decades (2002-2022).

Jajar SetiawanDicky Moch RizalFajar SofyantoroDwi Sendi PriyonoNur Indah SeptrianiWulan Usfi MafirohTakenori KotaniTakashi MatozakiWahyu Aristyaning Putri
Published in: Regenerative medicine (2024)
Aim: This study aimed to evaluate the trends in organoid culture research within the field of regenerative medicine from 2002 to 2022. Methods: The worldwide distribution of organoid research in regenerative medicine articles indexed in the Scopus database was analyzed. Result: A total of 840 documents were analyzed, averaging 42 publications annually. The USA (n = 296) led in publications, followed by China (n = 127), Japan (n = 91) and the UK (n = 75). Since 2011, research has surged, particularly in China, which emerged as a prominent center. Conclusion: The findings highlight significant growth in organoid research, promising future organ transplantation. Research trends integrate tissue engineering, gene modification and induced pluripotent stem cell technologies, reflecting a move toward personalized medicine.
Keyphrases
  • tissue engineering
  • stem cells
  • diabetic rats
  • copy number
  • drug induced
  • current status
  • emergency department
  • cell therapy
  • oxidative stress
  • mesenchymal stem cells
  • transcription factor
  • endothelial cells