A comparison of timing and patterns of treatment failure, and survival outcomes after progression between HPV+ and HPV- patients undergoing chemoradiation for oropharyngeal squamous cell carcinomas.
Francisco LaxaguePeter Y F ZengDorsa ZabihiNaif FnaisMohammed AlshahraniKevin FungS Danielle MacNeilAdrian MendezJohn YooJoseph S MymrykJohn W BarrettDavid A PalmaAnthony Charles NicholsPublished in: Head & neck (2023)
HPV+ OPSCC patients relapse later compared to HPV- patients in local/locoregional and distant sites. HPV+ patients with local/locoregional recurrence experience superior survival after recurrence, which does not hold true for isolated regional recurrences or distant metastases. These data can be useful to inform prognosis and guide treatment decisions in patients with recurrent OPSCC.
Keyphrases
- high grade
- end stage renal disease
- ejection fraction
- newly diagnosed
- patients undergoing
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- lymph node
- squamous cell
- cervical cancer screening
- radiation therapy
- patient reported outcomes
- machine learning
- free survival
- combination therapy
- deep learning
- electronic health record
- replacement therapy