Non-Enzymatic Amperometric Glucose Sensor Based on Carbon Nanodots and Copper Oxide Nanocomposites Electrode.
Tharinee SridaraJantima UpanSaianand GopalanAdisorn TuantranontChanpen KaruwanJaroon JakmuneePublished in: Sensors (Basel, Switzerland) (2020)
In this research work, a non-enzymatic amperometric sensor for the determination of glucose was designed based on carbon nanodots (C-dots) and copper oxide (CuO) nanocomposites (CuO-C-dots). The CuO-C-dots nanocomposites were modified on the surface of a screen-printed carbon electrode (SPCE) to increase the sensitivity and selectivity of the glucose sensor. The as-synthesized materials were further analyzed for physico-chemical properties through characterization tools such as transmission electron microscopy (TEM) and Fourier-transform infrared spectroscopy (FTIR); and their electrochemical performance was also studied. The SPCE modified with CuO-C-dots possess desirable electrocatalytic properties for glucose oxidation in alkaline solutions. Moreover, the proposed sensing platform exhibited a linear range of 0.5 to 2 and 2 to 5 mM for glucose detection with high sensitivity (110 and 63.3 µA mM-1cm-2), and good selectivity and stability; and could potentially serve as an effective alternative method of glucose detection.
Keyphrases
- reduced graphene oxide
- blood glucose
- hydrogen peroxide
- molecularly imprinted
- carbon nanotubes
- fluorescent probe
- gold nanoparticles
- high throughput
- electron microscopy
- label free
- nitric oxide
- metabolic syndrome
- adipose tissue
- skeletal muscle
- insulin resistance
- mass spectrometry
- high resolution
- ionic liquid
- tandem mass spectrometry