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New insights of Nb2O5-based coatings on the 316L SS surfaces: enhanced biological responses.

Jéferson Aparecido MoretoRogério Valentim GelamoMarcos Vinicius da SilvaTeresa Tromm SteffenCarlo José Freire de OliveiraPatrícia Andressa de Almeida BuranelloMarcelo Rodrigues Pinto
Published in: Journal of materials science. Materials in medicine (2021)
This communication aims to propose new insights of Nb2O5-based coatings on the 316L SS surface with great prospects to be used in the dentistry field as brackets. The Nb2O5 thin film was incorporated into the 316L SS by using PVD method. For this purpose, the studied system was characterized structurally and morphologically by using AFM, FTIR-IRRAS, Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). Biological assays were performed using human gingival fibroblast cell-line HGF-1. In agreement with FTIR and Raman results, the XPS technique indicates that Nb is present in an oxidation state assigned to Nb2O5. Furthermore, the coatings produced by PVD technique are less toxic and induces less inflammation in gingival cells (cell-line HGF-1), suggesting the strategy of use Nb2O5 thin film to cover the 316L SS promoted since its protection of the physiological environment to its biocompatibility improvement.
Keyphrases
  • raman spectroscopy
  • high resolution
  • induced apoptosis
  • endothelial cells
  • oxidative stress
  • high throughput
  • hydrogen peroxide
  • magnetic resonance
  • nitric oxide
  • current status
  • solid state
  • endoplasmic reticulum stress