Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer.

Yi-An ChengTung-Ho WuYun-Ming WangTian-Lu ChengI-Ju ChenYun-Chi LuKuo-Hsiang ChuangChih-Kuang WangChiao-Yun ChenRui-An LinHuei-Jen ChenTzu-Yi LiaoEn-Shuo LiuFang-Ming Chen

Published in: Journal of nanobiotechnology (2020)

mPEG × HER2, therefore, provided a simple one-step formulation to confer HER2-specific targeting and enhanced sensitivity and contrast intensity on HER2 positive tumors for multimodality imaging.

Keyphrases

high resolution
drug delivery
magnetic resonance
cancer therapy
magnetic resonance imaging
computed tomography
monoclonal antibody
contrast enhanced