Fontan protein-losing enteropathy is associated with advanced liver disease and a proinflammatory intestinal and systemic state.

Enrique Rodriguez de SantiagoLuis TéllezElvira Garrido-Lestache Rodríguez-MonteElena Garrido-GómezLara Aguilera-CastroMaría Álvarez-FuenteMaría Jesús Del CerroAgustín Albillos

Published in: Liver international : official journal of the International Association for the Study of the Liver (2020)

Fontan-PLE is associated with advanced liver disease and increased markers of systemic inflammation and intestinal permeability. Faecal calprotectin is elevated and correlates with Fontan-PLE severity. Liver assessment is mandatory in all Fontan patients, and especially in those with PLE.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
rheumatoid arthritis
systemic lupus erythematosus
patient reported outcomes
disease activity
amino acid
drug induced