A Novel Nanoconjugate of Landomycin A with C60 Fullerene for Cancer Targeted Therapy: In Vitro Studies.

V BilobrovV SokolovaS PrylutskaR PanchukO LitsisV OsetskyiMaxim P EvstigneevYu PrylutskyyM EppleU RitterJ Rohr

Published in: Cellular and molecular bioengineering (2018)

The obtained physico-chemical data indicate a complexation between the two compounds, leading to the formation of a C60 + LA nanocomposite. It was concluded that immobilization of LA on C60 fullerene enhances selectivity of action of this anticancer drug in vitro, indicating on possibility of further preclinical studies of novel C60 + LA nanocomposites on animal tumor models.

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